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The Timescale Dynamics of Epilepsies: From Seconds to Decades

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If you have a question about this talk, please contact Kirsty Shepherd .

Continuous long-term recordings (months to years) in patients with epilepsy directly show that seizures are regulated in a circadian manner in 80% of the cases. Besides, these recordings allowed to prove the presence of a much slower rhythm (days to weeks) of seizures. They strongly suggest the existence of specific molecular processes that influence the time of occurrence of seizures. I will show that cortical structures undergo dynamic reconfiguration of their molecular architecture in a daily manner in health and disease. Accounting for daily and multidien molecular rhythms is essential to our understanding of brain function and dysfunction.

This talk is part of the Electrical Engineering series.

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Lecture Theatre 1, Department of Chemical Engineering & Biotechnology, Philippa Fawcett Drive, Cambridge CB3 0AS Lecture Theatre, CRI Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge Lecture Theatre, Medical Research Council Cognition and Brain Sciences Unit

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