Implications and molecular mechanisms of MOK, a new signaling kinase in neurodegenerative neuroinflammation
- š¤ Speaker: Dr Cintia Roodveldt University of Seville
- š Date & Time: Friday 10 November 2023, 12:30 - 13:30
- š Venue: Seminar Room (Level 2), Dept of Pharmacology
Abstract
Dr Cintia Roodveldt
University of Seville
Biography
After graduating in Biotechnology (Universidad Nacional del Litoral, Argentina, 1999), Dr Roodveldt completed a PhD (2005, The Weizmann Institute of Science, Israel; Dan S. Tawfikās lab) in the field of āenzyme evolution and emergence of new enzyme functionsā. She then undertook a Postdoc at Prof. Chris M. Dobsonās lab (University of Cambridge, 2006-2009), investigating the āmolecular mechanisms of Hsp70 chaperone system and a-synuclein aggregates linked to Parkinsonās diseaseā.
In 2009 she joined David Pozoās lab, a neuroimmunology lab, at CABIMER Center (Seville, Spain) and started a new line of research on the effect of protein aggregates in innate immunity. Since 2012, and having attained competitive tenure track positions (e.g. āRamón y Cajalā Researcher), they have led a research team studying the āmechanisms of microglial neuroinflammation triggered by a-synuclein aggregates and novel immunization strategies in Parkinsonā. Her current research lines focus on the āidentification of new signalling pathways and therapeutic targets related to immune dysregulation in neurodegenerative diseases, particularly ALS and Parkinsonā.
Zoom link: https://zoom.us/j/97143593246?pwd=ckVsZFo2ZGlPei8vVGhoWXg1L0w5QT09
Meeting ID: 971 4359 3246
Passcode: LkGiwj915c
Series This talk is part of the Department of Pharmacology Seminar Series series.
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Dr Cintia Roodveldt University of Seville
Friday 10 November 2023, 12:30-13:30