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Measuring chaos: ongoing chromosomal instability in cancer through the lens of single-cell DNA sequencing

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If you have a question about this talk, please contact Igor Kavrakov .

Chromosomal instability is a characteristic hallmark of cancer, providing part of the genomic variation that makes cancer so heterogeneous and hard to treat. Here, we introduce the notion of recent copy number aberrations – a way to measure ongoing chromosomal instability using single-cell whole-genome DNA sequencing. Ultimately, this will contribute to a better understanding of the fundamental mechanisms and processes underlying chromosomal instability, and has the potential to improve patient care in the future.

This talk is part of the Darwin College Science Seminars series.

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