University of Cambridge > Talks.cam > Morphogenesis Seminar Series > Building and extending the body axis: the role of tissue Interfaces

  Browse A-Z

Log in

Googledetails Microsoftdetails

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹ️ Information

Building and extending the body axis: the role of tissue Interfaces

Download to your calendar using vCal

If you have a question about this talk, please contact Jia CHEN .

Abstract:

The formation of the body axis is a central step in embryonic development; however, how tissues coordinate to shape and extend it remains largely unknown. Using mouse gastruloids and Xenopus explants, we investigated how tissue interactions drive axis elongation. In gastruloids, we demonstrate that the mechanical properties at tissue interfaces drive collective cell flows and contribute to axis formation and early extension. In Xenopus explants, we show that coordinated interactions between epithelial and mesenchymal layers are essential for robust elongation. These findings highlight different but potentially conserved strategies by which tissues build and extend the body axis, revealing that tissue interfaces can organize coherent axis formation even in the absence of external signals.

This talk is part of the Morphogenesis Seminar Series series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Cambridge Carbon Nanotechnology Society CMS Meeting Room 3 Lecture Theatre 0, Baker Building, Trumpington Street

Other talks

LCLU Annual Talk: The Early Aqueous Environment of Mars Inferred From Mission Lifetime Results by the Curiosity Rover at Gale Crater title abstract tbc Director's Welcome The Neurophenomenology of Surrender: Agency, Renewal, and Social Engagement in Speaking in Tongues Why people with schizophrenia die earlier? Mortality and accelerated ageing An Amphibious Urbanism | | Cut 4: The Desert Arrives Slowly
 

© 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity