University of Cambridge > Talks.cam > MRC Mitochondrial Biology Unit Seminars > The role of mitochondrial transcriptional processes in modulating human health and disease

The role of mitochondrial transcriptional processes in modulating human health and disease

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Mitochondrial dysfunction is implicated in a wide range of human diseases, yet its causal role and the reasons for tissue-specific manifestations remain poorly understood. Here we show, using large-scale genetic and transcriptomic data, that nuclear regulation of mitochondrial gene expression contributes to complex trait biology. Our analyses reveal tissue-dependent mechanisms linking mitochondrial processes to disease risk and highlight opportunities for understanding and potentially targeting mitochondrial contributions to human health.

This talk is part of the MRC Mitochondrial Biology Unit Seminars series.

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