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Combining synthetic biology platforms for broad-spectrum influenza vaccine development

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If you have a question about this talk, please contact Fiona Roby .

Influenza A viruses (IAVs), the cause of flu, are respiratory pathogens circulating between humans and zoonotic reservoirs. Annual seasonal outbreaks, occasional global pandemics and sporadic zoonotic IAV infections contribute to substantial mortality and morbidity worldwide. Due to rapid antigenic evolution of the viral glycoproteins, licensed, strain-specific seasonal influenza vaccines exhibit suboptimal effectiveness despite annual reformulations. In this thesis, I explore synthetic biology platforms for vaccine antigen design and delivery to develop and assess broad-spectrum influenza immunogens in mice.

This talk is part of the Pre-viva talks Dept of Veterinary Medicine series.

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