Approximation of the individual Fisher information matrix and its use in design of population PK/PD studies
- đ¤ Speaker: Leonov, S (GlaxoSmithKline)
- đ Date & Time: Friday 12 August 2011, 09:45 - 10:30
- đ Venue: Seminar Room 1, Newton Institute
Abstract
We continue a discussion started at PODE 2010 meeting about different types of approximation of the individual Fisher information matrix and their use in design of population PK/PD studies which are described by nonlinear mixed effects models. We focus on several Monte Carlo-based options and provide examples of their performance.
Series This talk is part of the Isaac Newton Institute Seminar Series series.
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Friday 12 August 2011, 09:45-10:30