Abstract

In the cell, DNA is copied to messenger RNA , and triplet codons (64) in the messenger RNA are decoded to synthesize polymers of the natural 20 amino acids. This process (DNA to RNA to protein) is the ‘central dogma’ of molecular biology. Dr Chin’s team is interested in re-writing the central dogma to create organisms that synthesize proteins containing building blocks beyond the 20 natural amino acids. In his talk he will discuss the invention and synthetic evolution of new components to address the major challenges of re-writing the central dogma, as well as the application of these approaches for investigating and synthetically controlling diverse biological processes.

Register today; http://aaas-science.org/forms/MbrEvnt_ReprogramGenetic_111006