University of Cambridge > Talks.cam > BSS Formal Seminars > Using bespoke fluorescence microscopy to study the soft matter of living cells at the single molecule level

  Browse A-Z

Log in

Googledetails Microsoftdetails

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹ️ Information

Using bespoke fluorescence microscopy to study the soft matter of living cells at the single molecule level

Download to your calendar using vCal

If you have a question about this talk, please contact Tracy Inman .

The use of bespoke imaging tools and analysis can offer significant insight into the living counterpart of soft condensed matter. The soft matter of biological systems consists of molecular building blocks, a staple of which is protein. Protein molecules, so small that 1 billion would fit on the full-stop at the end of this sentence, carry out most of the vital activities in living cells. Many of these processes require the assembly of multiple proteins into remarkable biological machines. Obtaining the blueprints for the architecture of these machines is essential for understanding the workings of the cell. Here, I will discuss recent biological physics experiments on functional single-celled organisms in which one can apply bespoke fluorescence microscopy imaging and analysis to monitor the number and dynamics of several different proteins at the nanometre length scale to a precision of single molecules. 1

1. Reyes-Lamothe R, Sherratt DJ, Leake MC. Stoichiometry and architecture of active DNA replication machinery in Escherichia coli. Science. 2010, 328, 498-501.

This talk is part of the BSS Formal Seminars series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Online Hopkinson Meeting Room Zoom details: https://zoom.us/j/92447982065?pwd=RkhaYkM5VTZPZ3pYSHptUXlRSkppQT09

Other talks

Theophilus Richmond’s The First Crossing: The Transition from Slavery to Indentureship in the Caribbean and the Case of the Black Slave on the Hesperus Haematology and Palliative Care Title to be confirmed Proteomics: Expression Analysis and Subcellular Localisation Title to be confirmed Reproducibility In Astrophysical Simulations: The AGORA Initiative and a 14-Year Human Experiment (In Memory of Joel Primack)
 

© 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity