Selection and clonal interference in a seasonal influenza virus
- 👤 Speaker: Chris Illingworth (Sanger)
- 📅 Date & Time: Monday 18 February 2013, 11:30 - 12:30
- 📍 Venue: DD48, Cripps Court, Queens' College
Abstract
Time-resolved genomic data provide a valuable insight into rapidly evolving populations. However, identifying the effects of selection from such data is not always straightforward, particularly where alleles at multiple genetic loci are simultaneously under selection. I describe a method for estimating the strength of selection acting at multiple polymorphic loci, and discuss its use to evaluate selection, and between-allele interference effects, in the evolution of the seasonal influenza virus H3N2 .
Series This talk is part of the Worms and Bugs series.
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Chris Illingworth (Sanger)
Monday 18 February 2013, 11:30-12:30