University of Cambridge > Talks.cam > Isaac Newton Institute Seminar Series > Randomization for small clinical trials

  Browse A-Z

Log in

Googledetails Microsoftdetails

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹī¸ Information

Randomization for small clinical trials

Download to your calendar using vCal

If you have a question about this talk, please contact .

Design and Analysis of Experiments

Rare disease clinical trials present unique problems for the statistician designing the study. First, the trial may be small to reflect the uniquely small population of diseased in the population. Hence, the usual large sample beneficial properties of randomization (balancing on unknown covariates, distribution of standard tests, converging to a target allocation) may not apply. We describe the impact of such trials on consideration of randomization procedures, and discuss randomization as a basis for inference. We conclude that, in small trials, the randomization procedure chosen does matter, and randomization tests should be used as a matter of course due to its property of preserving the type I error rate under time trends.

This talk is part of the Isaac Newton Institute Seminar Series series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Oatley Meeting Room 1, Engineering, Department of Average on weekdays: 8972.67705736 kWh DAMTP atmosphere-ocean

Other talks

The Gardens of the Western Cape Polar Oceans Seminar Talk Group Work Shape modes of CP^1 vortices Secrets of the Surface: The Mathematical Vision of Maryam Mirzakhani ( EDI Film Screening) LMB Seminar - Mechanisms of mRNA packaging and export
 

Š 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity