Registry Studies in Organ Donation and Transplantation
- ๐ค Speaker: Professor Dave Collett, Associate Director of Statistics and Clinical Studies, Director of NHSBT Clinical Trials Unit
- ๐ Date & Time: Wednesday 13 January 2016, 13:00 - 14:00
- ๐ Venue: Thomas Strangeways Room, Strangeways Research Laboratory
Abstract
Much of the evidence used to inform the development of organ transplantation in the UK comes from analyses of observational data that make up a centrally maintained registry. After a brief overview of the UK Transplant Registry, maintained by NHS Blood and Transplant, the use of this Registry in the development of a new liver allocation scheme will be described and illustrated. The talk will cover the formulation of an allocation scheme based on transplant benefit, the need to adjust survival models that underpin the scheme to account for informative censoring, and the relative merits of new allocation arrangements. The use of updated marker data on disease severity, and the development of an index of the quality of a donated liver will also be described.
Series This talk is part of the BTRU Seminar Series series.
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Professor Dave Collett, Associate Director of Statistics and Clinical Studies, Director of NHSBT Clinical Trials Unit
Wednesday 13 January 2016, 13:00-14:00