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Flow-induced aggregation and clogging in a microfluidic channel following a Buchwald-Hartwig amination reaction

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If you have a question about this talk, please contact Alexei Lapkin .

Solid handling is an important issue in flow chemistry and represents a special challenge in micro reactors, which are readily subject to clogging due to their reduced size. Here, we investigate solid formation under laminar flow in a microfluidics geometry following a Buchwald-Hartwig amination reaction. Particulate morphology changes in a flow-dependent manner going from rosettes of needle-like crystals to more compact structures. Clogging time was also found to depend on the applied flow rate.

This talk is part of the Chemical Engineering and Biotechnology Departmental Seminars series.

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