University of Cambridge > Talks.cam > Genetics Seminar > Defining transcription units across the human genome.

  Browse A-Z

Log in

University Account External (via Google)

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹī¸ Information

Defining transcription units across the human genome.

Download to your calendar using vCal

If you have a question about this talk, please contact Caroline Newnham .

Host: Michaela Frye

The dramatic achievement of sequencing the whole human genome has been tempered by the subsequent realisation that the human transcriptome is far more complex than initially anticipated; far from any clear understanding of how and why it is made. My lab has focused on the basic mechanism of transcriptional termination and associated RNA 3 ’ end processing by the major RNA polymerase II (Pol II) that is responsible for the synthesis of all pre messenger RNA and most non coding RNAs. We have uncovered a surprising diversity of termination mechanisms using gene specific analyses. We are now applying new native elongating transcription (NET) sequencing strategies to define all Pol II transcription units (especially mammalian NET -seq). Using this technology we are uncovering unanticipated mechanistic cross talk between the basic transcription process and associated pre-mRNA and long non coding RNA processing.

This talk is part of the Genetics Seminar series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Quantum Matter Journal Club Zoom Webinar: please register to receive details http://bit.ly/CCHSR The Lecture Room, Department of Architecture

Other talks

Organiser Welcome A scientists guide to the art of radiation therapy and Neurosurgery for the oncologist Group Work Spectral rigidity of random covers of compact hyperbolic surfaces Title to be confirmed Quantum graphs with a time asymmetry: spectral optimization and spectral statistics
 

Š 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity