University of Cambridge > Talks.cam > Babraham Seminar > "Mechanosensitive regulation of cancer epigenetics and pluripotency"

  Browse A-Z

Log in

Googledetails Microsoftdetails

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹī¸ Information

"Mechanosensitive regulation of cancer epigenetics and pluripotency"

Download to your calendar using vCal

If you have a question about this talk, please contact Bobbie Claxton .

If you would like to attend this seminar, please contact us to arrange site access

Cell adhesion to the extracellular matrix governs virtually every aspect of cell behaviour. Integrins are the main cell adhesion receptors capable of triggering activation of downstream signalling pathways and enabling cells to sense the stiffness of their microenvironment. Force transmission to the cellular cytoskeleton triggers mechanochemical signalling influencing cell proliferation, gene expression and cell morphology. In my seminar I will describe how matrix stiffness regulates epigenetics and transcription in cancer cells and how mechanical coupling of the cytoskeleton to matrix is essential for maintenance of pluripotency in hPSC.

This talk is part of the Babraham Seminar series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Glass Room, Betty & Gordon Moore Library seminars Cambridge Centre for Analysis talks

Other talks

Kirk Public Lecture: Title TBC In conversation: Louis Herns Marcelin and Ola Osman on legacies of enslavement and contemporary violence in Liberia and Haiti Online Causal Inference Seminar Understanding the Interplay between LLMs' Utilisation of Parametric and Contextual Knowledge Title TBC An Amphibious Urbanism | | Cut 4: The Desert Arrives Slowly
 

Š 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity