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Protein misfolding and aggregation, from test tube to disease

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If you have a question about this talk, please contact Leonor Miller-Fleming .

Protein misfolding and aggregation into amyloid fibrils occurs in a variety of human pathologies, including Alzheimer’s and Parkinson’s diseases, amyotrophic lateral sclerosis, and diabetes type II. In this masterclass, known structures of amyloid fibrils, and detailed insights into protein aggregation kinetics in vitro will be discussed, highlighting the biophysical methods that are commonly used in such studies.

Talks will focus on protein misfolding and aggregation in a biological context. Taking yeast and C. elegans as examples, the speakers will present the use of model organisms to address the relationship between protein misfolding and disease.

This talk is part of the "Life Sciences Masterclass" series.

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