![[Search]](/static/images/search.gif){kind=small}
![[A-Z Index]](/static/images/az.gif){kind=small}
![[Contact]](/static/images/contact.gif){kind=small}
![[University of Cambridge]](/static/images/identifier2.gif){kind=small}
![[Talks.cam]](/static/images/talkslogosmall.gif)
Dr. Dimitri Chirgadze, Crystallography and Bioinformatics Group, Department of Biochemistry
Thursday 18 October 2007, 14:15-14:45
Protein Crystallisation
- đ¤ Speaker: Dr. Dimitri Chirgadze, Crystallography and Bioinformatics Group, Department of Biochemistry
- đ Date & Time: Thursday 18 October 2007, 14:15 - 14:45
- đ Venue: Board Room, Department of Chemical Engineering
Abstract
A critical phase in an X-ray structural determination process is the crystallisation of the purified protein. Not only is this step time-consuming, it also requires a considerable amount of protein sample. The main objective is to obtain large, preferably single well-ordered crystals capable of diffracting X-rays to the highest possible resolution. In this paper I will describe the theory, physical methods and strategy involved in the crystallisation of biological macromolecules, and also the work that has been done to crystallise two distinct proteins – HR1b domain of PRK1 (Protein Kinase C-Related Kinase 1) and NK1 fragment of HGF /SF (Hepatocyte Growth Factor/Scatter Factor).
Series This talk is part of the Chemical Engineering and Biotechnology occasional seminars series.
Included in Lists
- All Talks (aka the CURE list)
- Board Room, Department of Chemical Engineering
- CamBridgeSens
- Cambridge talks
- Chemical Engineering and Biotechnology
- Chemical Engineering and Biotechnology occasional seminars
- Featured lists
- ME Seminar
- School of Technology
- Trust & Technology Initiative - interesting events
- yk449
Note: Ex-directory lists are not shown.