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Jill Banfield, University of California, Berkeley
Monday 27 November 2023, 11:00-12:00
Crick Lecture 2023: Innovating metagenomics to explore the strange world of archaeal extrachromosomal elements
- 👤 Speaker: Jill Banfield, University of California, Berkeley
- 📅 Date & Time: Monday 27 November 2023, 11:00 - 12:00
- 📍 Venue: In person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom, link: https://mrc-lmb-cam-ac-uk.zoom.us/j/96751041497?pwd=SDgyU1NMdjFVdENscUZqams4Z1RWUT09
Abstract
Metagenomic methods have brought to light huge, diverse, linear extrachromosomal elements of Archaea that are referred to as Borgs, given their propensity to assimilate DNA from diverse organisms. Borgs clearly replicate in anaerobic methane-oxidizing archaea yet cannot easily be classified as either viruses or plasmids. We are applying new short read genome curation methods, long-read sequencing information and in silico structural biology tools to comprehensively define their genomes and uncover functions in their enigmatic proteomes. The findings indicate unexpected, highly replicated capacities that alter our perception of these strange, and likely biogeochemically important, entities.
Series This talk is part of the MRC LMB Seminar Series series.
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