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Small Angle X-ray Scattering: sample preparation, data collection, and data analysis.

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SAXS is a quick & easy technique that can give structural information about a macromolecule. However, it is extremely sensitive to sample quality. In addition, because of the limited amount of data, SAXS is also prone to being over interpreted and can easily lead to incorrect models. Therefore, I will discuss how to collect high quality SAXS data, how to discriminate ‘good’ data from ‘bad’ data, and how to get useful structural information out of a single SAXS curve.

This talk is part of the Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery series.

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