![[Search]](/static/images/search.gif){kind=small}
![[A-Z Index]](/static/images/az.gif){kind=small}
![[Contact]](/static/images/contact.gif){kind=small}
![[University of Cambridge]](/static/images/identifier2.gif){kind=small}
![[Talks.cam]](/static/images/talkslogosmall.gif)
Professor Eric Westhof (Institut de Biologie MolΓ©culaire et Cellulaire du CNRS, UniversitΓ© de Strasbourg).
Wednesday 20 February 2019, 16:00-18:00
xyp20's list
A personal list of talks.
Contact: 23791
0 upcoming talks View 167 archived talks
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
tRNA Modifications and Decoding Errors
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
A Saposin-lipoprotein nanoparticle system for membrane proteins
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Capturing the 3D Folds of Whole Mammalian Genomes in Single Cells
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Protein:protein recognition in the Ubiquitin Proteasome-degradation System (UPS) and Membrane Surface Complexes from the Ras-family
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structural studies of a DNA unwinding machine
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Architecture of PIKK Kinases and their molecular mechanisms of regulation
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Protein and Peptide Mass Spectrometry Analysis
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Solution-based angular measurements of protein structure and conformational change by second-harmonic generation (SHG)
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Fragment based inhibition of CK2Ξ±
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Correlative tweezers fluorescence microscopy: one step towards real-time single-molecule biology
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Substrate reduction enabled by structural biology as therapy for metabolic disorders
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Toward the Reconstitution of the Maturation of Okazaki Fragments Multiprotein Complex in Human at the Single Molecule Level
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Using Computational Structure Biology to Study Diseases that cause Major Health Concerns in Brazil
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Not Too Big - Not Too Small: Fragment Antibody Drug Candidates as Alternatives to Antibodies for Solid Tumours
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Mycobacterium Tuberculosis Physiology: The Intricate Interplay between Drug Tolerance and Drug Resistance
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Shortening Tuberculosis Chemotherapies: Elucidating the Molecular genetic programs of persistence of M. tuberculosis
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Human 2-oxoacid-dependent Oxygenases
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The simple reason that M. avium subspecies paratuberculosis has been missed as a major human pathogen is that, unknowingly, it's been treated since 1942
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Signalling through interleukin/interferon receptors: outside and inside of the cell
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Linking Structural Biology and Clinical Genomics: Purine Nucleotidase in Relapsed Leukemia
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Revolutionary Cryo-EM: the Potential Power to Visualize High Resolution Dynamic Structures
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Rebuilding the HDX-MS Method to Support Integrative Methods in Structural Biology
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
High-Throughput Fragment-Based Drug Discovery at Diamond Synchrotron: Robots can do much of the work to screen in FBDD!
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
COSMIC Catalogue of Cancer Mutations and the 3D Proteome
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Dynamic interactions and fuzzy structures in protein complexes and higher-order assemblies
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Using Integrative Methods in Structural Biology to Understand Protein Structure
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Computational study of mutations in proteins
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Myc and MexR: conformational selection and fuzzy complexes in transcriptional regulation
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
What's new at PDBe?
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Phosphoproteomic strategies reveal global impact of kinase inhibitors on regulatory kinase networks and the phosphoproteome
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
A computational framework for optimizing combination drug therapies
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structure and Function of TIFA - A New Player in Immunity and Cancer
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Interactive molecular dynamics for improved model building and exploration in structural biology
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Predicting the impact of natural and disease variants on protein function
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Targeting Trehalose and Methylglucose Lipopolysaccharide Pathways of M. tuberculosis
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
TBC
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Matching density maps of macromolecular assemblies from Cryo-EM and assessment of fitted atomic models
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The 3D structures of genomes in single cells reveal principles of nuclear organization
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The E. coli replisome caught in the act by cryo-EM and single molecule microscopy
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Pregnancy outcome prediction using placenta epigenetic data
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Protein transport to the endoplasmic reticulum
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Computational approaches to investigate protein-nucleic acid and protein-protein interactions
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Mapping of ligand binding site and activation mechanism of APJ receptor
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Dr Paul Brear - Inhibiting CK2Ξ± from outside the active site
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Prof Song Tan - TBC
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Fitting atomic structures into EM density maps
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Migle Kisonaite - "Structure of Gremlin-1: Insights into the Mechanism of Bone Morphogenetic Protein Antagonism" and Xuelu Wang "Understanding of the Pro-domain in TGF-Ξ² Superfamily: Structure and Characterisation of Pro-activin A"
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
ARCIMBOLDO, an ab initio approach to MR phasing
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Atomic resolution cryoEM structure of bacteriophage
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Modulating Protein-Protein Interactions
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Title to be confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structural Biology and Transmembrane Signalling: Understanding a 'Double-edged' Receptor, DCC
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Impact of rapid whole-genome sequencing on diagnostic and public health microbiology
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structural Mechanisms in Protein Kinase Regulation
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Predicting drug-target binding kinetics through enhanced sampling simulations
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Biodiversity and Drug Discovery
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Recent advances in high resolution cryo-EM structure determination
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Dr Meindert Lamers - Title to be confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Dr Isaac Westwood - Title to be Confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Dr Christian Ottmann, Title to be confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Investigating the human proteasome by cryo-EM - an emerging tool for structural based drug design
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Dr Takashi Ochi and Dr Qian Wu
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Tools for refinement against low resolution X-ray data and fit to EM reconstructions
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Identification and characterization of interaction sites with MD simulations of mixed solvents β Application to non-standard targets
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
(1) An introduction to Gene Synthesis - capabilities and uses. (2) An introduction to precise genome editing with TAL effectors and CRISPR
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Support Science and Diamond Light Source
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Professor Randy Read - title to be comfirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structures and mechanisms of macromolecular complexes involved in transcription and DNA repair
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Crystal structure of the Drosophila Toll-SpΓ€tzle complex reveals neurotrophin-like binding specificity
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
How insulin binds to the insulin receptor: structural biology and protein engineering
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The Structure of the Large Subunit of the Yeast Mitochondrial Ribosome
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Coot's EM Model-fitting Tools
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Small Angle X-ray Scattering: sample preparation, data collection, and data analysis.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Cyclofluidic: Quick hit-to-lead optimization using an integrated microfluidic approach
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Title to be confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Using evolutionary sequence variation to make inferences about protein structure and function
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Protein-Protein Interaction Networks and Diseases
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Analysis of allosteric communication and functional local motions using a Structural Alphabe
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Chirality as a crossroad of chemistry and biology
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Title to be confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Evolution & dynamics of protein complexes
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Crystallisation and structure of respiratory complex I, a giant molecular proton pump
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Probing dynamic conformational changes in lipid signalling using hydrogen deuterium exchangemass spectrometry
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Open Source Drug Discovery:Β Developing a Systems LevelΒ Translational Platform for Neglected Diseases
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
PHASER workshop
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
OPPF-UK: a national resource centre for protein production.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
AnchorQuery: Interactive and efficient discovery tool of small molecule protein-protein interaction antagonists
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Identifying hot-spots and designing small molecule inhibitors at protein-protein interfaces: taking advantage of bound water networks
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The importance of thermostability and its application to the structure determination of GPCRs
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
X-ray diffraction data reduction: space group determination, scaling and intensity statistics
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Title to be confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structural studies of chromosome segregation
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
SAXS studies on biological molecules at Diamond Light Source
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Domain swapping in proteins
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
To be confirmed
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Low Resolution Crystallography
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Making candy for signal transduction research - Adventures in Willy Wonka land
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Low resolution refinement tools in the program REFMAC
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Fuzzy complexes: ambiguity in protein-protein and protein-DNA interactions
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structural complexomics of eukaryotic gene expression.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Receptor-based Drug Discovery
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Probing protein-ligand recognition mechanisms with isothermal titration calorimetry
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Crystal dehydration: Experimental design with a home source and at the synchroton
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Designing Bioactive Molecules and Mode-of-Action Analyses - The Benefits of Learning From the Past.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Drug Protein Interaction Databases
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The Ghosts of PDBe Past, Present Β and Yet to Come
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
i-SITE: An energetic approach to predict ligand-binding site on protein surface
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The rational design of small-molecule Neuropilin-1 antagonists
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Restraints on Protein Models from NMR Chemical Shifts
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Software for fragment linking and growing.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Using Biacore for fragment screening
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Off-site Targets: Predicting drug polypharmacology using ligand similarity ensembles.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Targetting Protein-Protein Interactions: Synergies between NCEs and New Antibodies.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Fragment-based drug discovery using X-ray crystallography.
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Can machines understand the Scientific Literature?
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Inter-molecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric back-protonation and 2D NOESY
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Engineering proteins for fragment screening
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Surface Plasmon Resonance
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
STING_DB
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Drug-protein Databases: ZINC, Credo,Β CHEMBL
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Fragments versus traditional screening . Off-targetΒ analysis
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
ITC
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
X-ray single soaks or cocktails? GrowingΒ versus Linking.Β
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Targetting PPI
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Recap of Experimental Fragment-based projects
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Completely in vitro protein engineering automation
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Molecular recognition - from single target to protein complexes
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
HIV-1 Reverse Transcriptase: Structure, Drug Resistance, and Drug Design
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The microseed matrix screening method for protein crystallisation
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Electrochemically-assisted protein crystallisation: Applications to biosensors
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Public domain medicinal chemistry data at the EBI and the use in drug discovery
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The influence of electric and magnetic fields to increase the crystal quality of proteins
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The role of impurities in protein crystallisation: advantages and disadvantages
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Protein Crystal Growth in Gels and Capillary Tubes
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Conventional and non-conventional methods of protein crystal growth
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Recent adventures in protein folding and design
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Leaving drinks for Sheena
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
SPR - theory and practise
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Biocore
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Expression systems for protein complexes
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Pathway-based analysis of genome-wide siRNA screens
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Party for Richard and Timo
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Fragment-based Screening and It's Role in Ontario Cancer Institute
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Molecular Puzzles: Learning About Function and Mechanism of Enzymes From their Structures
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Convergence of Molecular Epidemiology, Functional Biology and Host-pathogen Interactions: Zeroing on Potential Drug Targets for M. TUBERCULOSIS
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
test
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Neurotrophic factors in Drosophila
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Small hydrogen-bonded motifs in proteins and their significance for amyloid formation
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structural chemistry in the pharmaceutical industry: view from a returned exile
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
DNA site-specific recombination: Architecture of a recombinase
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Mechanisms of Transmembrane Transport: towards structures of membrane protein drug targets
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Toll like receptors - Investigating innate immunity and infection
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
High intrinsic binding specificity mediates the interactions of a yeast SH3 domain
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Expriences in Structure-based Discovery
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Fragment based drug discovery - from crystal to clinic
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Paradoxical Features of Nicotinic Receptor
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
New protein purification columns and media from GE Healthcare
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
UCB Approaches to Drug Discovery, A Focus on 2 Cambridge projects
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
Structural basis of fatty acid synthesis catalyzed by giant multienzyme complexes
Experimental and Computational Aspects of Structural Biology and Applications to Drug Discovery
The long and the short: virulence proteins from Staphylococcus and Streptococcus
Please see above for contact details for this list.